β-Conglutins’ Unique Mobile Arm Is a Key Structural Domain Involved in Molecular Nutraceutical Properties of Narrow-Leafed Lupin (Lupinus angustifolius L.)

European Research Program MARIE CURIE (FP7-PEOPLE- 2011-IOF), grant ref. PIOF-GA-2011-301550The Spanish Ministry of Economy, Industry and Competitiveness (Ramon y Cajal Research Program)Grant ref. RYC-2014-16536The CSIC intramural research program, grant ref. 202240I002The Spanish Ministry of Science and Innovation, grant ref. number CPP2021-00898

Estrategias de enseñanza y rendimiento escolar en el área de inglés en los estudiantes del VI ciclo de Educación Secundaria de la I.E. Gustavo Mohme Llona, Ate, 2014

El presente estudio titulado “Estrategias de enseñanza y rendimiento escolar en el área de inglés en los estudiantes del VI ciclo de Educación Secundaria de la I.E. Gustavo Mohme Llona, Ate, 2014” se realizó con el objetivo de Determinar la relación que existe entre las estrategias de enseñanza y el rendimiento escolar en el área de inglés; y se desarrolló en un contexto escolar del nivel secundario de la I.E. N° 1268 Gustavo Mohme Llona, Ate, 2014. Es una investigación descriptiva correlacional de diseño no experimental transversal de nivel correlacional, aplicó un instrumento (cuestionario) para medir la variable estrategias de enseñanza y fue validado mediante juicio de expertos y sometido a la prueba de confiabilidad, para medir la variable rendimiento escolar del área de inglés se utilizaron los registros de notas. La muestra estuvo conformada por 123 estudiantes. Las conclusiones existe relación significativa entre las estrategias de enseñanza y el rendimiento escolar en el área de inglés en los estudiantes del VI ciclo de educación secundaria de la I.E. N° 1268 Gustavo Mohme Llona, Ate, 2014, con un nivel de significancia de 0.05 y Rho de Spearman = 0.894 y p-valor = 0.000 < 0.05

Globalización y modernidad en la política en América Latina

This paper shows the need to link contemporary political processes with Latin American modernity or modernities. Its characteristic plurality will define operating permanences and changes in four main categories: politics, state, citizenship and civil society. All those concepts are directly influenced by globalization and neoliberal discourse. In this perspective, the phenomenon of globalization will be understood as a factor, which can organize or deorganize the abovementioned categories.El presente trabajo sostiene la necesidad de vincular los procesos políticos contemporáneos con la modernidad o las modernidades latinoamericanas. La pluralidad constitutiva de ella va definir las permanencias y transformaciones que van a operar en cuatro categorías claves: política, Estado, ciudadanía y sociedad civil. Todas ellas tensionadas por la globalización y el discurso neoliberal. En esta perspectiva el fenómeno de la globalización será entendido como factor que va a desordenar y a ordenar las categorías antes mencionadas

Factores socioculturales y efectos de plomo en sangre en niños de 6 meses a 12 años puesto de salud Champamarca, Pasco, 2018.

La presente investigación tuvo como objetivo determinar la relación que existe entre los factores socioculturales y los efectos de plomo en sangre en niños de 6 meses a 12 años, en el Puesto de Salud Champamarca, Pasco- 2018. El método utilizado fue descriptivo, el diseño correlacional de corte transversal, de tipo cuantitativo. La muestra estuvo conformada por 68 madres de niños de 6 meses a 12 años. Para la recolección de datos se utilizó el cuestionario y una ficha de recolección de datos de la historia clínica, la cual tuvo una confiabilidad de Alfa de Cronbach total de 0.876 y de 0.784.The present academical research have has as an objective to determine the relationship that exist between sociocultural factors and the effects of the lead in the blood of children under 6 months to 12 years old at the Health Center Chapamarca in Pasco, 2018. The method used was descriptive, the cross-sectional correlational design, quantitative type. The study sample consisted of 68 mothers who has children of 6 months old to 12 years old. Also, for data collection it has been used the questionnaire and a a record of data collection of the clinical history, which has a reliability of the Cronbach's Alpha of 0.876 and 0.784

Optical Responses of Localized and Extended Modes in a Mesoporous Layer on Plasmonic Array to Isopropanol Vapor

Mesoporous silica features open and accessible pores that can intake substances from the outside. The combination of mesoporous silica with plasmonic nanostructures represents an interesting platform for an optical sensor based on the dependence of plasmonic modes on the refractive index of the medium in which metallic nanoparticles are embedded. However, so far only a limited number of plasmonic nanostructures are combined with mesoporous silica, including random dispersion of metallic nanoparticles and fl at metallic thin fi lms. In this study, we make a mesoporous silica layer on an aluminum nanocylinder array. Such plasmonic arrangements support both localized surface plasmon resonances (LSPRs) and extended modes which are the result of the hybridization of LSPRs and photonic modes extending into the mesoporous layer. We investigate in situ optical re fl ectance of this system under controlled pressure of isopropanol vapor. Upon exposure, the capillary condensation in the mesopores results in a gradual spectral shift of the re fl ectance. Our analysis demonstrates that such shifts depend largely on the nature of the modes; that is, the extended modes show larger shifts compared to localized ones. Our materials represent a useful platform for the fi eld of environmental sensingEspaña MINECO grant MAT2017-88584-R

Performance analysis of persistence technologies for cloud repositories of models

The growing adoption of Model Driven Development (MDD) in companies during last decade arises some model interchange problems. Companies need support to interchange models and reuse parts of them for developing new projects. Traditional tools for model edition and model interchange have different performance issues related to the models storage. There are mainly two styles to organize the persistence of models into repositories: a complex and large model or a large amount of small models. This last approach is common in companies that generate software from models. In this paper, we analyse performance properties of different persistence technologies to store small/medium-scale models, the analysis results should be considered in the design of model repositories in the cloud. With this aim, we have designed and developed a generic architecture to evaluate each persistence technology under similar situations

Comparación del rendimiento productivo de pollos de engorde suplementados con tylosina fosfato versus enramicina como promotores de crecimiento

Evalúa el rendimiento productivo de pollos de engorde suplementados con tylosina fosfato y enramicina como promotores de crecimiento. Se usaron 400 pollos machos de engorde de 1 día de edad, divididos en 4 tratamientos de 100 animales con 5 repeticiones cada uno. El tratamiento 1(T1), control; dieta sin antibiótico promotor de crecimiento; Tratamiento 2 (T2), dieta con antibiótico enramicina al 8% en dosis máxima de 10 ppm; Tratamiento 3 (T3), dieta con antibiótico enramicina al 8% en dosis mínima de 5 ppm; Tratamiento 4 (T4), dieta con antibiótico tilosina fosfato al 25% en dosis máxima de 55 ppm. El diseño experimental usado es el irrestricto al azar. Fueron evaluados los parámetros productivos: peso corporal, consumo de alimento, ganancia de peso, índice de conversión alimenticia (ICA) e índice productivo Europeo (IEPE). A los 42 días de edad, el T4 obtuvo 161 gramos más de peso corporal que el control, 49 gramos más que el T2 y 34 gramos más que el T3, se demostró diferencia estadística significativa sobre los pesos corporales entre el grupo control contra los tratamientos 2, 3, 4. Respecto a la conversión alimenticia, a la sexta semana el T2 presentó 118 puntos menos que el control, 28 puntos menos que el T3 y 18 puntos menos que el T4. El tratamiento control mostró diferencia significativa con el resto de los tratamientos. El mejor índice de eficiencia productiva europeo (IEPE) a los 42 días de edad, lo obtuvo el T4 con una diferencia de 62.98 puntos más sobre el control, 20.07 sobre el T3 y 17.34 sobre el T2. El tratamiento control mostró diferencia significativa con el resto de los tratamientos. El mejor rendimiento productivo fue obtenido en las aves suplementadas con Tilosina fosfato a la dosis máxima (55 ppm).Tesi

The effect of the crisis on the economic federative situation and evolution of sports results in Spain

Sports federations are the great promoters of sport at the national level. Their public-private structure requires them to maintain a strong relationship with the public administration. That is why the economic situation of a country, as well as the sports support policy, significantly influence the structure, projects and sports results obtained. This work shows the evolution of public funding in the Spanish federative sport, as well as the evolution of the medals obtained in the Olympic Games held in the period 2008-2017

The effect of the crisis on the economic federative situation and evolution of sports results in Spain

Sports federations are the great promoters of sport at the national level. Their public-private structure requires them to maintain a strong relationship with the public administration. That is why the economic situation of a country, as well as the sports support policy, significantly influence the structure, projects and sports results obtained. This work shows the evolution of public funding in the Spanish federative sport, as well as the evolution of the medals obtained in the Olympic Games held in the period 2008-201

Crosstalk between chromatin structure, cohesin activity and transcription

Background: A complex interplay between chromatin and topological machineries is critical for genome architec‑ ture and function. However, little is known about these reciprocal interactions, even for cohesin, despite its multiple roles in DNA metabolism. Results: We have used genome‑wide analyses to address how cohesins and chromatin structure impact each other in yeast. Cohesin inactivation in scc1‑73 mutants during the S and G2 phases causes specific changes in chromatin structure that preferentially take place at promoters; these changes include a significant increase in the occupancy of the − 1 and + 1 nucleosomes. In addition, cohesins play a major role in transcription regulation that is associated with specific promoter chromatin architecture. In scc1‑73 cells, downregulated genes are enriched in promoters with short or no nucleosome‑free region (NFR) and a fragile “nucleosome − 1/RSC complex” particle. These results, together with a preferential increase in the occupancy of nucleosome − 1 of these genes, suggest that cohesins promote transcription activation by helping RSC to form the NFR. In sharp contrast, the scc1‑73 upregulated genes are enriched in promoters with an “open” chromatin structure and are mostly at cohesin‑enriched regions, suggesting that a local accumulation of cohesins might help to inhibit transcription. On the other hand, a dramatic loss of chromatin integrity by histone depletion during DNA replication has a moderate effect on the accumulation and distribution of cohesin peaks along the genome. Conclusions: Our analyses of the interplay between chromatin integrity and cohesin activity suggest that cohesins play a major role in transcription regulation, which is associated with specific chromatin architecture and cohesin‑ mediated nucleosome alterations of the regulated promoters. In contrast, chromatin integrity plays only a minor role in the binding and distribution of cohesins.Spanish Ministry of Economy and Competitivenes BFU2012-38171, BFU2015-63698-PAndalusian Government P12-CTS-227